Buy Cipro Malaysia

Package insert: Information for the user

Cipro 250 mg film-coated tablets Cipro 500 mg film-coated tablets Cipro 750 mg film-coated tablets

Equivalent medicine

Read this leaflet carefully before you start taking this medicine because it contains important information for you.

- Keep this leaflet. You may need to read it again.

• If you have any further questions, ask your doctor or pharmacist.
• This medicine has only been prescribed for you. Do not pass it on to others, even if the symptoms of the disease are the same as yours, as this can be dangerous.
• If you experience side effects, including those not listed in this leaflet, contact your doctor or pharmacist.

Contents of this brochure:

1. What is Cipro and what is it used for?
2. What you need to know before taking Cipro
3. How to take Cipro
4. possible side effects
5. How to store Cipro
6. Contents of the pack and other information

1. What is Cipro and what is it used for?

   Cipro is an antibiotic from the fluoroquinolone family. The active substance is ciprofloxacin. Ciprofloxacin kills bacteria that cause infections. It can only affect certain strains of bacteria.

   Adults

   Cipro is used in adult subjects to treat the following bacterial infections:

   • Respiratory infections
   • long-lasting or recurring ear and nose infections
   • Urinary tract infections
   • Testicular infections
   • Genital organ infections in women
   • Gastrointestinal infections and intra-abdominal infections
   • Skin and soft tissue infections
   • Bone and joint infections
   • to treat infections in patients with a very low number of white blood cells (neutropenia)
   • to prevent infections in patients with a very low number of white blood cells (Neutropenia)
   • for the prevention of infections caused by the Neisseria meningitidis bacterium

   Inhaled anthrax exposure: If you have a serious infection or an infection caused by more than one type of bacteria, you may be given additional antibiotic treatment in addition to Cipro.

   Children and adolescents

   Cipro is used in children and adolescents under the supervision of a specialist to treat the following bacterial infections:

   • Lung and bronchial infections in children and adolescents with cystic fibrosis
   • complicated urinary tract infections, including those that have reached the kidneys (pyelonephritis)
   • Inhaled anthrax exposure: Cipro can also be used to treat other specific serious infections in children and adolescents when the doctor thinks it is necessary.

2. What you need to know before taking Cipro Do not take Cipro:

   • if you are allergic to ciprofloxacin, other quinolone medicines, or any of the other ingredients in this medicine (see section 6).
   • if you are taking tizanidine (see section 2: Other medicines and Cipro).

   Warnings and precautions

   Talk to your doctor, nurse, or pharmacist before taking Cipro if you:

   • Have heart problems. Caution should be exercised when using this type of medicine if you are born with a prolonged QT interval or if you have a family history (indicated on the ECG, an electrical record of the heart), an imbalance of saline in the blood (especially a low value of Potassium or magnesium in the blood), a very slow heart rhythm (called bradycardia), a weak heart (heart failure), a history of a heart attack (myocardial infarction) if you are a woman or an elderly patient or if you are taking other medicines that abnormal ECG changes (see section Other Medicines and Cipro)
   • I have had kidney problems as an adjustment may be required treatment
   • suffer from epilepsy or other neurological diseases
   • In the past, you had tendon problems with previous antibiotic treatments such as Cipro

   Have myasthenia gravis (a type of muscle weakness)

   During treatment with Cipro

   Tell your doctor straight away if the following happens during treatment with Cipro. Your doctor will decide whether to stop treatment with Cipro.

   • Sudden severe allergic reaction (anaphylactic reaction / shock, angioedema). Already at the first dose, there is a low probability that a severe allergic reaction will occur with the following symptoms: chest tightness, drowsiness, discomfort or fainting or dizziness when standing up. In this case, stop taking Cipro and contact your doctor immediately.

   • Pain and swelling of the joints and tendinitis may occasionally occur.

     especially if you are older and are also being treated with corticosteroids. Stop taking Cipro at the first sign of pain or inflammation and leave the affected area alone. Avoid unnecessary effort as this can increase the risk of tendon rupture. Tendonitis and ruptures can also occur up to several months after stopping treatment with Cipro.

   • If you have epilepsy or other neurological conditions such as ischemia or cerebral stroke, you can do so obvious side effects related to the central nervous system. In this case, stop taking Cipro and contact your doctor immediately.
   • Psychiatric reactions may occur the first time you take Cipro. If you have depression or psychosis, your symptoms may get worse during treatment with Cipro. In this case, stop taking Cipro and contact your doctor immediately.
   • It can manifest symptoms of neuropathy such as pain, burning, tingling, numbness and / or weakness. In this case, stop taking Cipro and contact your doctor immediately.
   • Diarrhea may occur during treatment with antibiotics, including ciprofloxacin even a few weeks after stopping treatment. If this becomes severe or persistent, or if you find that your stool contains blood or mucus, stop taking Cipro immediately as it can be dangerous for your life. Do not take medicines that block or slow bowel movements and contact your doctor.
   • If you need to provide blood or urine samples, tell your doctor or laboratory staff who takes cipro.
   • Cipro can cause liver damage. If you experience symptoms such as loss of appetite, jaundice (yellowing of the skin), dark urine, itching or stomach pain, stop taking Cipro and contact your doctor immediately.

   Cipro can reduce the number of white blood cells

   Resistance to infection can be reduced. If you have an infection with symptoms such as fever and a serious deterioration in your general condition or fever with symptoms of a local infection such as sore throat / mouth ulcers or urinary problems, you should see your doctor immediately. A blood test should be done to see if white blood cells are reduced (agranulocytosis). It is important to tell the doctor about the medicine you are taking.

   Tell your doctor if you or one of your family members have glucose-6 deficiency.

   Phosphate dehydrogenase (G6PD) because it harbors anemia when taken with ciprofloxacin.

   • Your skin becomes more sensitive to sunlight or ultraviolet (UV) rays when you take it Cipro. Avoid strong sunlight or artificial UV light such as sun beds.

     Other medicines and cipro

     Tell your doctor or pharmacist if you are taking, have recently taken, or may be taking other medicines.

     Do not take Cipro with tizanidine as this can cause side effects such as low blood pressure and drowsiness (see section 2: Do not take Cipro).

     You must tell your doctor if you are taking other medicines that can change your heart rhythm: antiarrhythmic drugs (e.g. quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide), tricyclic antidepressants, some antimicrobials ( which belong to the group of macrolides), some antipsychotics.

     The following medicines are known to interact with Cipro in your body. Taking Cipro with these medicines can affect their therapeutic effects. In addition, this can increase the possibility of side effects.

     Tell your doctor if you are taking any of the following:

   • Warfarin, acenocoumarol, phenprocoumon, fluindione or other oral anticoagulants (used to dissolve blood)
   • Probenecid (for gout)
   • Metoclopramide (for nausea and migraines)
   • Omeprazole (for stomach ulcers, indigestion, heartburn and Zollinger-Ellison syndrome)
   • Cyclosporin (an immunosuppressant)
   • Methotrexate (for some cancers, psoriasis, rheumatoid arthritis)
   • Theophylline (for breathing problems)
   • Tizanidine (for muscle spasticity in multiple sclerosis)
   • Clozapine (an antipsychotic)
   • Ropinirole (for Parkinson's)
   • Phenytoin (for epilepsy)
   • Olanzapine (an antipsychotic)
   • Glibenclamide (for diabetes)

   Cipro may increase the levels of the following medicines in your blood:

   • Pentoxifylline (for circulatory disorders)
   • caffeine
   • Lidocaine (an anesthetic)
   • Sildenafil (for erectile dysfunction)
   • Duloxetine (for depression, anxiety, pain and stress incontinence) some medicines reduce the effects of Cipro. Tell your doctor if you are taking or want to take the following:
   • Antacids
   • Mineral supplements
   • Sucralfate
   • a polymeric phosphate binder (e.g. Sevelamer)
   • Medicines or supplements that contain calcium, magnesium, aluminum, or iron

   If these preparations are essential, take Cipro at least two hours before and at least four hours after.

   Cipro with food and drink

   If you do not take Cipro with meals, you must not eat or drink milk derivatives (such as milk or yoghurt) or take calcium-enriched drinks while taking the tablets, as these can affect the absorption of the active substance.

   pregnancy and breast feeding period

   It is preferable to avoid using Cipro during pregnancy.

   Do not take Cipro while breastfeeding, as ciprofloxacin is excreted in breast milk and can be dangerous for your baby.

   If you are pregnant, breast-feeding, planning to become pregnant, or plan to breast-feed, ask your doctor or pharmacist for advice before taking this medicine.

   Drive and use machines

   Cipro can reduce your attention. Some neurological adverse events can occur. Therefore, make sure that you respond to Cipro before driving a vehicle or using machinery. If you have any doubts, talk to your doctor.

3. How to take Cipro

   Your doctor will explain exactly what dose of Cipro to take and how often and how long to take it. This depends on the type of infection affected and its severity.

   Tell your doctor if you have kidney problems, as this may require a dose adjustment.

   Treatment usually lasts 5 to 21 days, but can take longer in severe infections.

   Always take this medicine exactly as your doctor or pharmacist has told you. If you are not sure, contact your doctor or pharmacist.

   1. Swallow the tablets with plenty of fluids. Do not chew the tablets because they do not taste pleasant.
   2. Try to take the tablets at the same time each day.
   3. You can take the tablets with or between meals. The calcium that you eat during meals does not seriously affect your intake. However, do not take Cipro tablets with dairy products such as milk or yoghurt or with fortified fruit juices (e.g. calcium-fortified orange juice).

   Remember to take Cipro while drinking plenty of fluids.

   If you take more Cipro than you should

   If you take a higher dose than the one prescribed, see a doctor straight away. If possible, take the tablets or their packaging with you to show your doctor.

   If you forget to take Cipro

   Take the normal dose as soon as possible and then continue as directed. However, if it is almost time for the next dose, do not take the missed dose and continue as usual. Do not take a double dose to make up for a forgotten dose. Make sure you complete the course of treatment.

   If you stop taking Cipro

   It is important that the course of treatment ends, even if it feels better after a few days. If you stop taking this medicine too soon, your infection may not be completely cured and your symptoms may come back or get worse. It can also develop antibiotic resistance.

   If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. possible side effects

   Like all medications, this medication can cause side effects, although not everyone gets them.

   Common side effects (may affect up to 1 in 10 people):

   • Nausea, diarrhea
   • Joint pain in children

   Uncommon side effects (may affect up to 1 in 100 people):

   • Fungal super infections
   • a high concentration of eosinophils, a type of white blood cell
   • Loss of appetite (anorexia)
   • Hyperactivity or restlessness
   • Headache, dizziness, sleep disturbance or taste disturbance
   • Vomiting, abdominal pain, digestive problems such as stomach pain (indigestion / heartburn) or aerophagia
   • Increase in the amount of certain substances in the blood (transaminase and / or bilirubin)
   • Rash, itching or hives
   • Joint pain in adults
   • poor kidney function
   • Muscle and bone pain, malaise (asthenia) or fever
   • increased alkaline phosphatase in the blood (a certain substance found in the blood)

   Rare side effects (may affect up to 1 in 1,000 people):

   • Inflammation of the bowel (colitis) associated with the use of antibiotics (which can be very lethal in very rare cases) (see paragraph 2: warnings and precautions)
   • Changes in blood values (leukopenia, leukocytosis, neutropenia, anemia), increase or decrease in the values of a blood coagulation factor (platelets)
   • allergic reaction, swelling (edema) or rapid swelling of the skin and mucous membranes (angioedema)
   • increased blood sugar (hyperglycaemia)
   • Confusion, disorientation, fear reactions, changed dreams, depression, which in rare cases can lead to thoughts of suicide or behavior or suicide or hallucinations
   • Tingling sensation, unusual sensitivity to sensory stimuli, decreased skin sensitivity, tremors, cramps (see section 2: Warnings and precautions) or drowsiness
   • Vision problems
   • Tinnitus, hearing loss, hearing problems
   • fast heartbeat (tachycardia)
   • Dilation of the blood vessels (vasodilation), low blood pressure or fainting
   • Shortness of breath, including symptoms of asthma
   • Liver disease, jaundice (cholestatic jaundice) or hepatitis
   • Sensitivity to light (see section 2: Warnings and precautions)
   • Muscle pain, joint inflammation, increased muscle tone or cramps
   • Kidney failure, blood or crystals in the urine (see section 2: Warnings and precautions), inflammation of the urinary tract
   • Fluid retention or excessive sweating
   • increased levels of the amylase enzyme

   Very rare side effects (may affect up to 1 in 10,000 people):

   • a special way of reducing the number of red blood cells (hemolytic anemia); a dangerous decrease in the number of white blood cells (agranulocytosis); a dangerous decrease in the number of white, red blood cells and platelets (pancytopenia), which can be fatal; and bone marrow depression, which can also be fatal (see section 2: Warnings and precautions)
   • severe allergic reactions (anaphylactic reactions or anaphylactic shock, which can be fatal - serum sickness) (see section 2: Warnings and precautions)
   • mental disorders (psychotic reactions), which in rare cases can lead to thoughts of suicide or suicidal behavior (see section 2: warnings and precautions)
   • Migraines, coordination disorders, uncertain step (gait disorder), olfactory disorders (olfactory disorders), intracranial pressure (intracranial pressure)
   • visual distortion of colors
   • Inflammation of the walls of blood vessels (vasculitis)
   • Pancreatitis
   • Liver cell death (liver necrosis), which very rarely can lead to life-threatening liver failure
   • small bleeding under the skin (petechiae); various types of rash or rash (e.g., potentially fatal Stevens-Johnson syndrome or toxic epidermal necrolysis)
   • Muscle weakness, inflammation of the tendons, fracture of the tendons - especially the large tendons on the back of the ankle (Achilles tendon) (see section 2: warnings and precautions); Worsening of symptoms of myasthenia gravis (see section 2: warnings and precautions)

     Frequency not known (cannot be estimated from the available data)

   • Problems related to the nervous system such as pain, burning, tingling, numbness and / or weakness in the extremities
   • Heart problems abnormal accelerated heart rhythm, life-threatening irregular heart rhythm, changed heart rhythm (called "QT interval extension", shown on the ECG, electrical activity of the heart)
   • Generalized acute exanthematous pustulosis (AGEP) - skin disease with red blisters on the skin
   • Increased blood thinning when taking anticoagulants like warfarin if you get any side effects, including those not listed in this leaflet, contact your doctor, pharmacist or nurse.

5. How to store Cipro

   Keep this medicine out of the sight and reach of children.

   Do not use this medicine after the expiry date which is stated on the label or packaging after "EXP". The expiry date refers to the last day of this month.

   This medicine does not require special storage conditions.

   Do not throw medication into wastewater or household waste. Ask your pharmacist how to get rid of medicines you no longer use. This helps protect the environment.

6. Contents of the pack and other information What Cipro contains

• The active substance is ciprofloxacin (as ciprofloxacin hydrochloride).

Each film-coated tablet contains 250 mg ciprofloxacin (as ciprofloxacin hydrochloride).

Each film-coated tablet contains 500 mg ciprofloxacin (as ciprofloxacin hydrochloride).

Each film-coated tablet contains 750 mg ciprofloxacin (as ciprofloxacin hydrochloride).

Advertising - The other components are:

Tablet core: microcrystalline cellulose, sodium glycolate starch (type A), povidone (K 30), silicon dioxide (colloidally anhydrous), magnesium stearate.

Coating film: hypromellose, macrogol (400), titanium dioxide.

Description of the appearance of Cipro and the contents of the pack

Film-coated tablet

Cipro 250 mg

Round, white or almost white, film-coated tablets with a cut line on one side and the inscription "F" and "23" on the other side, separated by a cut line.

The cut line is said to help break the tablet if you have difficulty swallowing it completely and not dividing it into two equal parts.

Advertising '

Cipro 500 mg

Capsule-shaped, white or almost white film-coated tablets with a cut line on one side and the imprint "F 22" on the other side.

The tablet can be divided into equal parts.

Cipro 750 mg

Capsule-shaped, white or almost white film-coated tablets, marked "C" on one side and "93" on the other side.

PVC / PVDC blister coated with aluminum foil, packed in a box. Packaging:

250 mg and 750 mg: 6, 10, 12, 14, 16, 20, 28, 50, 100 and 120 film-coated tablets

500 mg: 1, 6, 10, 12, 14, 16, 20, 28, 50, 100 and 120 film-coated tablets It is possible that not all pack sizes will be marketed.

This brochure was last updated on 02/2020. Medical information / recommendations

Antibiotics are used to treat bacterial infections. They are ineffective against viral infections. If your doctor has prescribed antibiotics for you, this is exactly what you need for the disease you are suffering from. Despite antibiotics, some bacteria can survive or grow. This phenomenon is called resistance: some antibiotic treatments become ineffective. The wrong use of antibiotics increases resistance. It is even possible that you will help the bacteria become resistant and therefore delay your treatment or reduce the effectiveness of the antibiotic if you do not comply with the relevant provisions:

• Cans
• Dosage plans
• Duration of treatment

To maintain the effectiveness of this medicine:

1 - Use antibiotics only on prescription. 2 - Follow the regulations closely.

3 - Do not use an antibiotic without a prescription, even if you want to treat a similar disorder. 4 - Never give your antibiotic to anyone else. may not be appropriate for your illness. 5 - Return all unused medicines to a pharmacy after treatment is complete so that they are properly eliminated.