Buy Nolvadex Malaysia

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Active ingredient: Tamoxifen
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Nolvadex is a Medicine to Protect Women
The main reason of death of women in Great Britain and in the world is breast cancer. There are also more and more young people who suffer from breast cancer. The range of their ages is from 13 years old to 90 years old. Currently, there is one in eight women in the world suffering from breast cancer.
It is very interesting that cases of breast cases are rarer then cases of lung cancer. Certainly, structures of female breast and male breast are similar but cases of male breast cancer are rarer then cases of female breast cancer.
Therefore, prevention, early detection, and medical treatment of breast cancer are the main problems of modern public health services.
Cancer prevention and cancer detection are not secret for the world medical community but it is more difficult to treat cancer.
It is possible to treat cancer in such various ways as surgery treatment, radiotherapy, and medical treatment including targeted therapy. However, these methods have indications, contraindications, and rather serious adverse effects. Therefore, fifty years ago, nobody could imagine that there would be low activity medicines acting against breast cancer.
About 100 years ago, there were already the preconditions for endocrine therapy of breast cancer. At the end of XIX century, scientists concluded that there were patients who suffered from hormone-dependent carcinoma.
A Scottish doctor George Batson was one of the first scientists who noticed and described this phenomenon and who proposed to use the oophorectomy method to treat breast cancer and suggested that human tumors could be treated in such a way.
In 1896, he also convinced that development of female tumor was slower and there were various reasons for oophorectomy. He noticed that the main estrogen source was ovaries and supposed that female sex hormones were reason for tumorous activity of breast. That was a reason for creating of antiestrogens.
Hormonotherapy against breast cancer was the basis of the discovery.

During the next 50 years, many physicians treated the tumor with different medicines. The next developments was hopeless because of adverse effects though some of them were successful.
In 1962, the specialists of the imperial Chemical Industries (ICI) Company made a bad antiestrogen substance while creating contraceptives.
Despite the team of the project wanted to continue to study creation of molecules and to establish the effect of the medicines acting against cancer tumors, there was no the following research and more priority activities of the company were a reason for that.
The state of affairs changed in the early 1970. One of the main constituents of research developments of world pharmaceutical companies was the cancer treatment. The ICI Company also began to produce drugs acting against cancer.
In 1971, in Manchester, there were the first clinical trials of the substance tamoxifen. So, action of the molecule against breast cancer was effective. This data was confirmed next year. An outstanding American scientist V.C. Jordan was non-official father of tamoxifen. That was he who suggested using tamoxifen for breast cancer prevention and developed the main principles of antihormone adjuvant therapy.
After two years, the ICI Company developed the drug successfully and began to sale tamoxifen in USA as the medicine Nolvadex acting against breast cancer. In 1977, the FDA approved tamoxifen as a medicine preventing development of breast cancer and as a medicine used for adjuvant therapy.
Many specialists confirmed that the tamoxifen discovery was a real breakthrough of oncology. However, there was vigilance caused by dependence of therapeutic benefit and side effect on a dose and duration of taking of the medicine. There is not still complete sureness that the treatment does not cause medicine resistance and medicine in susceptibleness, which are a reason for antimeoplastic action of the molecule to disappear.
The anxiety was a reason for the ICI Company to do extensive research basing to the results of which doses were determined and schemes of treatment were developed.
As it was a gold standard of treatment of breast cancer during more than 25 years, tamoxifen was a real breakthrough of oncology despite dependence of therapeutic benefit and side effect on a dose and duration of taking of the medicine.
During more than 25 years, there were many tractates, which registered reduced frequency of relapses and medicine mortality. According to the Oxford Reviews of the Joint Team of Early Stage of Breast Cancer Researchers, tamoxifen halved frequency of relapses of breast cancer (41%) and reduced breast cancer mortality a third (34%). There were no changed effects during about 15 years after it was diagnosed.
There was no any information about other methods of treatment long-term effect at relatively moderate toxicity and affordability of tamoxifen.
Tamoxifen was also the first medicine for prophylaxis of breast cancer of healthy women suffering from increased risk of development of breast cancer approved by the FDA in 1998.
In 2013, the Department of Health and Social Care of Great Britain developed a new program for prophylaxis of breast cancer. It published the first European manual for English and Wales physicians. According to the manual, women should take tamoxifen daily during five years. In their opinion, that would reduce a risk of development of breast cancer by 40%. The Department of Health and Social Care of Scotland supported this idea. May be, Irish scientists and physicians will also practice daily taking of tamoxifen during five years by women.
Until nowadays, they proposed medicines for women suffering from diagnosed breast cancer.
It is necessary to notice one more property of tamoxifen. You may found much information about the tamoxifen enrichment of food for body-builders and tamoxifen taking as a fat-burning medicine at the Internet!
In authors’ of the materials opinions, nowadays, tamoxifen - Nolvadex is the most popular antiestrogen among sportsmen and body-builders.
As Nolvadex acts to block estrogen effects, people combine it often with anabolic steroids.
Aromatase enzymes act to convert many steroids into estrogen causing an imbalance of ratio of androgens and estrogen causing retention of water in the organism. Increased estrogen level may also be a reason for male breast augmentation and increased subcutaneous fat layer covering muscles. Some body-builders take Nolvadex to fight against the symptoms. Nolvadex is still the cheapest and the most reasonable though recently a medicine of wider spectrum has been invented.
According to web and forum visitors, as Nolvadex maintains the process of fat burning because of its antiestrogen action, its action helps to keep a diet though it does not burn directly fat.
However, it is necessary to take Nolvadex during the breast cancer therapy.
That was why the WHO registered Nolvadex as a life-saving medicine acting against breast cancer.
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